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Methylprednisolone News

A phase I/II trial of pixantrone (BBR2778), methylprednisolone, cisplatin, and cytosine arabinoside (PSHAP) in relapsed/refractory aggressive non-Hodgkin's lymphoma

The purpose of the study was to evaluate the safety, efficacy, and pharmacokinetics of pixantrone (BBR2778) when substituted for etoposide in the ESHAP regimen in patients with aggressive relapsed or refractory non-Hodgkin's...

Cardioprotective Effects of Methylprednisolone Treatment in Cardiac Surgery: Presented at STS

Preoperative glucocorticoid therapy provides cardioprotective benefits to low-risk patients undergoing coronary artery bypass grafting (CABG), researchers said here at the 43rd Annual Society of Thoracic Surgeons (STS) Meeting in...

The Impact of Methylprednisolone on Lesion Severity Following Spinal Cord Injury

Objective. Determine if the administration of MPS immediately following SCI affects lesion severity.

Recurrent acute hepatitis in patient receiving pulsed methylprednisolone for multiple sclerosis

We report clinically significant, recurrent acute hepatitis in a 48-year-old woman receiving pulsed treatment with methylprednisolone for multiple sclerosis. No other cause was found for the episodes and the temporal and...

Pharmacogenomic Responses of Rat Liver to Methylprednisolone: An Approach to Mining a Rich Microarra

A data set was generated to examine global changes in gene expression in rat liver over time in response to a single bolus dose of methylprednisolone. Four control animals and 43 drug-treated animals were humanely killed at 16...

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